منابع مشابه
Divalent cation transport in kidney slices. I. Properties of calcium transport in slices of rat kidney cortex and the effects of diuretics.
Correlative studies on transports of Ca2+ and Na+ and the properties of Ca2+ transport were carried out in rat kidney cortex slices. Ouabain had no effect on the Ca2+ transport but did inhibit the Na+ transport extensively. With addition of 2,4-dinitrophenol to the incubation medium, or under the anaerobic conditions, the effluxes of Ca2+ and Na+ were inhibited while the Ca2+ influx was enhance...
متن کاملDivalent cation transport by VNUT DIVALENT CATION TRANSPORT BY VESICULAR NUCLEOTIDE TRANSPORTER
The vesicular nucleotide transporter (VNUT) is a secretory vesicle protein that is responsible for the vesicular storage and subsequent exocytosis of ATP (Sawada, K. et al., (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 11720-11724). Since VNUT actively transports ATP in a membrane potential (Δψ)-dependent manner irrespective of divalent cations such as Mg or Ca, VNUT recognizes free ATP as a trans...
متن کاملEffects of divalent cations on prostaglandin biosynthesis and phospholipase A2 activation in rabbit kidney medulla slices.
The divalent cations Ca2+, Mg2+, Co2+, Mn2+, Sr2+, and Ba2+ were compared for their stimulatory or inhibitory effect on PG formation in rabbit kidney medulla slices. Calcium, manganese, and strontium ions stimulated PG generation up to 3- to 5-fold in a time- and dose-dependent manner (Ca2+ greater than Mn2+ approximately Sr2+) while the magnesium and cobalt ions were without significant effect...
متن کاملCharacterization of Divalent Cation Dependence
An 4 1/ 4 7 dual antagonist, S-compound 1, was used as a model ligand to study the effect of divalent cations on the activation state and ligand binding properties of 4 integrins. In the presence of 1 mM each Ca /Mg , S-compound 1 bound to several cell lines expressing both 4 1 and 4 7, but 2S-[(1-benzenesulfonyl-pyrrolidine-2S-carbonyl)-amino]-4-[4methyl-2S-(methyl-{2-[4-(3-o-tolyl-ureido)-phe...
متن کاملA23187: a divalent cation ionophore.
A23187 is a carboxylic acid antibiotic which simultaneously uncouples oxidative phosphorylation and inhibits ATPase of rat liver mitochondria incubated in a magnesium-free medium. The antibiotic acts as a freely mobile carrier to transport calcium and magnesium, but not potassium, from an aqueous medium buffered at pH 7.4 into a bulk organic phase. A23187 causes a progressive release of endogen...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1980
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)31474-x